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《广州医药》编辑部
目的 观察超声引导下针刺蝶腭神经节治疗过敏性鼻炎的临床疗效。方法 将80例过敏性鼻炎患者随机分成干预组(40例)和对照组(40例),干预组采用超声引导针刺蝶腭神经节,对照组采用常规方法针刺蝶腭穴,每周2次,持续4周。结果 治疗4周后,干预组和对照组均显示出良好疗效。干预组的总有效率为92.50%,对照组的总有效率为82.50%,差异有统计学意义(P<0.05);干预组在鼻症状总分(TNSS)、非鼻症状总分(TNNSS)、视觉模拟量表(VAS)和鼻结膜炎生活质量问卷(RQLQ)等指标上的改善均优于对照组(P<0.05)。结论 超声引导下针刺蝶腭神经节治疗过敏性鼻炎能有效改善患者的临床症状。
Objective To investigate the main clinical effect of acupuncture of pterygopalatine ganglion on patients with allergic rhinitis under the guidance of ultrasound.Methods A total of 80 patients with allergic rhinitis were randomly divided into intervention group and control group.The intervention group was treated with ultrasound guided acupuncture of the sphenopalatineganglion,the control group was treated with conventional acupuncture at sphenopalatine point.The clinical efficacy was determined after the course of treatment.Results The total effective rate was 92.50% in the intervention group and 82.50% in the control group.The improvement of total nasal symptom score,total non-nasal symptom score,VAS and Arhinoconjunctivitis Quality of Life Questionnaire scores in the treatment group was significantly better the control group Conclusions Ultrasound-guided acupuncture of the sphenopalatine ganglion can improves clinical symptoms of patients with allergic rhinitis.
目的 评估ChatGPT 4与Llama 3微调模型在乳腺癌诊断中的应用效果,特别是在超声、钼靶及超声联合钼靶的非结构化报告和影像诊断方面。方法 回顾性收集了689例同时接受乳腺超声和钼靶检查的患者数据,比较两种模型在文本和图像模态下的诊断性能,并探讨乳腺密度对模型表现的影响。结果 在文本模态下,微调Llama 3表现优异,联合诊断准确率达91.7%,优于ChatGPT 4的71.7%。图像模态中两模型准确率均低于70%,但ChatGPT 4灵敏度较高(78.3%),Llama 3特异度突出(98.3%)。分组分析表明,在非致密型乳腺中钼靶表现更佳,而致密型乳腺中超声诊断更具优势。结论 大语言模型在医学图像处理和多模态整合方面仍需进一步优化,医学领域微调的大语言模型在处理非结构化临床文本方面具有潜力。
Objective To evaluate the application effectiveness of ChatGPT 4 and the fine-tuned Llama 3 model in breast cancer diagnosis,particularly in processing unstructured reports and diagnostic imaging of ultrasound,mammography,and their combined modalities.Methods Retrospective data from 689 patients who underwent both breast ultrasound and mammography examinations were collected.The diagnostic performance of the two models was compared across text and image modalities,and the impact of breast density on model performance was explored.Results In the text modality,the fine-tuned Llama 3 model performed excellently,achieving a combined diagnostic accuracy of 91.7%,outperforming 71.7% of ChatGPT 4.In the image modality,both models had accuracies below 70%,but ChatGPT 4 exhibited higher sensitivity(78.3%),while Llama 3 demonstrated outstanding specificity(98.3%).Subgroup analysis indicated that mammography performed better in non-dense breasts,whereas ultrasound was more advantageous in dense breasts.Conclusions The large language models still require further optimization in medical image processing and multimodal integration,but fine-tuned large language models in the medical field show potential in handling unstructured clinical texts.
目的 探讨经颅多普勒超声(TCD)参数联合屏气指数在颈内动脉(ICA)狭窄或闭塞所致急性脑梗死的评估价值。方法 选择2022年1月—2024年12月,在广州市花都区人民医院连续入组发病72 h内ICA狭窄或闭塞所致的急性脑梗死患者。记录患者人口统计学资料、临床资料及TCD相关参数,包括搏动指数(PI)、阻力指数( RI)、大脑中动脉平均血流速度(Vm)及屏气指数等。依据患者数字减影血管造影(DSA)结果分为侧支循环良好组及侧支循环不良组。比较两组人口统计学、临床资料及TCD相关参数,采用单因素分析、多因素Logistic回归分析及ROC曲线。结果 共纳入ICA狭窄或闭塞所致急性脑梗死共136例,其中侧支循环良好组46例,侧支循环不良组90例。单因素分析提示:侧支循环良好组与侧支循环不良组在PI[0.95(0.80,1.03)vs 1.01(0.88,1.13)]、RI[0.58(0.51,0.62)vs 0.60(0.54,0.65)]、Vm[57(44,65)vs 50.5(41,63)]及屏气指数[0.78(0.75,0.85)vs 0.72(0.59,0.79)]方面,差异具有统计学意义(P<0.05)。多因素Logistic回归分析提示Vm(OR=1.029,95%CI:1.006~1.053,P=0.014)、屏气指数(OR=723.401,95%CI:14.524~3 6031.859,P<0.001)是侧支循环不良的独立危险因素。屏气指数和Vm评估侧支循环情况的ROC曲线下面积(AUC)分别为0.713(95%CI:0.627~0.799)和0.605(0.505~0.705),两者的AUC值比较差异无统计学意义(P>0.05)。结论 屏气指数和Vm可以评估ICA狭窄或闭塞所致急性脑梗死的侧支循环,屏气指数和Vm的评估效能相当。
Objective To explore the evaluation value of transcranial Doppler ultrasound(TCD)in acute cerebral infarction caused by internal carotid artery(ICA)stenosis or occlusion.Methods From January 2022 to December 2024,patients with acute cerebral infarction caused by ICA stenosis or occlusion within 72 hours of onset were enrolled in our hospital.Patient’s demographic data,clinical data,and TCD related parameters,including pulsatility index(PI),resistance index(RI),average blood flow velocity(Vm)of the middle cerebral artery,and breath holding index(BHI)were recorded.According to the results of digital silhouette angiography(DSA),patients were divided into good collateral group and poor collateral group.Demographic,clinical data,and TCD related parameters were compared between two groups using univariate analysis,multivariate Logistic regression analysis and ROC curve.Results A total of 136 cases of acute cerebral infarction caused by ICA stenosis or occlusion were included,including 46 cases in the collateral good group and 90 cases in the collateral poor group.Univariate analysis showed that the good collateral group and the poor collateral group were different in PI(0.95[0.80,1.03]vs 1.01[0.88,1.13]),RI(0.58[0.51,0.62]vs 0.60[0.54,0.65]),Vm(57[44,65]vs 50.5[41,63]),BHI(0.78[0.75,0.85] vs 0.72[0.59,0.79])(P<0.05).Multivariate Logistic regression analysis showed that Vm(OR=1.029,95%CI:1.006-1.053,P=0.014)and BHI(OR=723.401,95%CI:14.524-36 031.859,P<0.001)were independent risk factors for collateral circulation disorders.The area under the ROC curve(AUC)for predicting collateral circulation using BHI and Vm were 0.713(95%CI:0.627~0.799)and 0.605(0.505~0.705),respectively.There was no statistically significant difference in AUC values between the BHI and Vm.Conclusions The BHI and Vm can predict the collateral circulation of acute cerebral infarction caused by ICA stenosis or occlusion,and their predictive power is comparable.
目的 探讨肌骨超声(MSUS)在慢性肌肉骨骼疼痛(CMP)康复精准化教学中的应用效果。方法 选取在广州市第一人民医院南沙医院康复医学科实习的43名大专及本科学生,对照组进行常规CMP康复精准化教学,MSUS组在常规教学基础上增加MSUS辅助教学。实习结束后,通过专业理论考试和实践考核观察教学效果,并以问卷调查学生对教学形式和效果的满意度。结果 MSUS组的理论考核成绩为(84.62±5.14)分,对照组为(81.45±6.21)分,两组间差异无统计学意义(P>0.05)。MSUS组的实践考核成绩(4.71±1.06)分高于对照组(3.64±1.14)分(P<0.05)。问卷调查显示,MSUS组学生的总体满意度(35.24±3.43)高于对照组(32.64±3.98),P<0.05。其中,对于教学方法的满意度,MSUS组(9.81±0.60)高于对照组(8.82±1.18)(P<0.05);对于综合分析与实践能力的满意度,MSUS组(7.43±1.91)高于对照组(6.18±1.62)(P<0.05)。结论 MSUS教学在夯实学生专业基础知识、深化临床实践、提高综合分析能力和学习积极性方面具有显著优势,为精准化康复教学提供了有效手段。
Objective To explore the application effect of musculoskeletal ultrasound(MSUS)in the precise teaching of chronic musculoskeletal pain(CMP)rehabilitation.Methods Forty-three college and undergraduate students interning in Rehabilitation Medicine Department of Nansha Hospital,Guangzhou First People’s Hospital were selected,control group conducted conventional CMP rehabilitation teaching,and the MSUS group received additional MSUS-assisted teaching on the basis of the conventional teaching.After the internship,the teaching effectiveness was observed through professional theoretical examinations and practical assessments,and a questionnaire survey was conducted to evaluate students’satisfaction with the teaching methods and outcomes.Results The theoretical assessment score of the MSUS group were(84.62±5.14)and(81.45±6.21)of the control group,there was no difference between the two groups(P>0.05).The practical assessment scores of the MSUS group(4.71±1.06)were higher than those of the control group(3.64±1.14),and a significant difference was found between the two groups(P<0.05).The questionnaire survey showed that the overall satisfaction of the MSUS group students(35.24±3.43)was higher than that of the control group(32.64±3.97)(P<0.05).Among them,satisfaction with the teaching method was higher in the MSUS group(9.81±0.60)than in the control group(8.82±1.18)(P<0.05),satisfaction with comprehensive analysis and practical ability was also higher in the MSUS group(7.43±1.91)than in the control group(6.18±1.62)(P<0.05).Conclusions MSUS teaching has significant advantages in consolidating students’basic professional knowledge,deepening clinical practice,improving comprehensive analysis ability and learning enthusiasm.It provides an effective means for precise rehabilitation teaching.
目的 探讨超声引导下腹横肌平面阻滞(TAP)联合无阿片药全身麻醉(全麻)在腹腔镜子宫全切术中的应用效果。方法 选取武威市凉州医院2021年5月—2023年5月收治的60例择期行腹腔镜子宫全切术患者展开前瞻性研究,应用抽签法将其分为观察组与对照组,各30例。对照组患者实施常规阿片类药物全麻,观察组采用TAP联合无阿片药全身麻醉。对比两组患者入室后(T0)、切皮时(T1)、手术10 min后(T2)和手术结束即刻(T3)生命体征变化,麻醉后监测治疗室(PACU)恢复情况,术后1、4、8、12、24、48 h疼痛程度,最后对比其48 h内不良反应发生率。结果 两组T0、T1、T2、T3时间血氧饱和度(SpO2),T0、T3时间平均动脉压(MAP)、心率水平无明显变化,两组对比差异无统计学意义(P>0.05),T1、T2时间对照组MAP、心率升高,观察组T1、T2的MAP、心率均低于对照组(P<0.05);观察组PACU停留时间、首次肛门排气时间明显低于对照组(P<0.05);观察组术后1、4、8、12、24、48 h活动时视觉模量表(VAS)评分与静息时VAS评分低于对照组(P<0.05);观察组术后48 h内不良反应发生率比对照组更低(P<0.05)。结论 针对腹腔镜子宫全切术患者采取超声引下TAP联合无阿片药全麻可稳定患者术中生命体征,缩短患者术后恢复时间,减轻疼痛程度,且可降低术后48 h内不良反应发生率。
Objective To explore the application effect of ultrasound-guided transverse abdominis plane(TAP)block combined with opioid-free general anesthesia in laparoscopic total hysterectomy.Methods A prospective study was conducted in 60 patients who underwent selective laparoscopic total hysterectomy in Wuwei Liangzhou Hospital from May 2021 to May 2023.They were divided into a observation group and a control group using a lottery method,30 cases in each group.The control group received routine opioid general anaesthesia,while the observation group received TAP in combination with opioid-free general anaesthesia.Comparing the changes of vital signs after invasion(T0),skin cutting(T1),10 min after operating(T2),the end of surgery(T3),and condition in the post-anesthesia care unit(PACU)after anesthesia,the pain degree at 1 h,4 h,8 h,12 h,24 h and 48 h after surgery,and the incidence of adverse reactions within 48 h.Results There were no significant changes in blood SpO2,mean arterial pressure(MAP)and heart rate at T0,T1,T2 and T3 in both groups,and no significant difference between the two groups(P>0.05).MAP and heart rate increased in the control group at T1 and T2,while those in the observation group were lower than the control group(P<0.05).The observation group had significantly shorter PACU time and first anal exhaust time than the control group(P<0.05).VAS scores at 1 h,4 h,8 h,12 h,24 h and 48 h after surgery and VAS score at rest in the observation group were lower than in the control group(P<0.05).The incidence of adverse reactions within 48 h after surgery was lower in the observation group than in the control group(P<0.05).Conclusions Ultrasound guided TAP combined with opioid-free general anesthesia can stabilize intraoperative vital signs,shorten postoperative recovery time,alleviate postoperative pain,and reduce the incidence of anesthesia related adverse reactions within 48 hours for patients undergoing laparoscopic total hysterectomy.
目的 探讨产时超声管理妊娠期糖尿病产妇产程的应用价值。方法 选择2022年1月1日—2023年12月31日在佛山市高明区人民医院妇产科分娩的妊娠期糖尿病初产妇共100例。患者签署知情同意书后, 按照1∶1比例采用随机数字表法分为对照组和研究组各50例。对照组采用阴道指诊检查判断产程和分娩方式。研究组采用经腹联合会阴超声测量检查判断产程及分娩方式。收集两组初产妇血糖、血常规、分娩方式、产后24 h出血量以及切口情况, 新生儿Apgar评分。结果 研究组阴道分娩率高于对照组(88.0% vs 72.0%, P<0.05), 而阴道检查次数(4.18±0.8 vs 6.82±0.8, P<0.05)少于对照组、不良事件发生率(4% vs 16%, P<0.05)低于对照组。相对于对照组,研究组血红蛋白水平较高(104.10±5.25 vs 100.30±4.78, P<0.05)、而白细胞计数(11.40±1.49 vs 12.04±1.66, P<0.05)以及中性粒细胞百分比较低(72.79±4.04 vs 75.01±5.53, P<0.05)。结论 通过产时超声监测判断妊娠期糖尿病初产妇产程,能够降低阴道操作引起的感染等风险,提高阴道分娩率,有效降低产妇感染,提高产妇分娩满意度以及舒适度,改善母婴结局。
Objective To explore the application value of intrapartum ultrasound for labor management of pregnant women with gestational diabetes mellitus.Methods A total of 100 primiparous women with gestational diabetes mellitus who gave birth in the Obstetrics and Gynecology Department of Foshan Gaoming District People’s Hospital from January 1, 2022 to December 31, 2023 were selected.After signing the informed consent form, the patients were randomly divided into a control group and a study group with 50 cases in each group according to a ratio of 1∶1, using a random number table method.The control group underwent vaginal digital examination to assess the labor process and delivery method.For the study group, the labor process and delivery mode were determined using transabdominal ultrasound measurement.Blood glucose level,routine blood test results, delivery methods, 24-hour postpartum bleeding volume and incision conditions of two groups of primiparas, as well as the Apgar score of newborns were collected.Results The study group demonstrated a significantly higher vaginal delivery rate than the control group(88.0% vs 72.0%, P<0.05), with fewer vaginal examinations(4.18±0.80 vs 6.82±0.80, P<0.05)and a lower incidence of adverse events(4% vs 16%, P<0.05).Compared to the control group, the study group exhibited higher hemoglobin levels([104.10±5.25]g/L vs [100.30±4.78] g/L, P<0.05), but lower white blood cell counts([11.40±1.49]×109/L vs [12.04±1.66]×109/L, P<0.05)and reduced neutrophil percentages([72.79±4.04]% vs [75.01±5.53]%, P<0.05).Conclusions Intrapartum ultrasound monitoring for assessing labor progression in primiparas with gestational diabetes mellitus reduces infection risks associated with vaginal procedures, increases vaginal delivery rates, effectively decreases maternal infections, enhances maternal satisfaction and comfort during delivery,and improves maternal-neonatal outcomes.
目的 探讨超声弹性成像联合高频超声在甲状腺乳头状癌诊断中的应用价值。方法 2022年1月—2023年6月选择在中国人民解放军联勤保障部队第九九〇医院诊治的疑似甲状腺乳头状癌患者82例,所有患者均给予超声弹性成像联合高频超声检查,记录超声特征。所有患者均行病理检查,并以病理检查作为判断的金标准。结果 在82例患者中,病理诊断为甲状腺乳头状癌48例(癌性组),占比58.54%;甲状腺良性结节34例(良性组),占比41.46%。癌性组的形态异常、后方回声衰减、钙化、晕环征、边界不清晰、内部低回声等超声征象占比为81.25%、83.33%、83.33%、83.33%、81.25%、81.25%,高于良性组的52.94%、47.06%、47.06%、41.18%、47.06%、52.94%(P<0.05)。癌性组的收缩期最高流速低于良性组(P<0.05),阻力指数、搏动指数与良性组相比有提高(P<0.05)。癌性组的弹性成像评分多为3~4分,良性组多为2分,两组比较差异有统计学意义(P<0.05)。超声弹性成像联合高频超声判断为甲状腺乳头状癌47例,诊断中的灵敏度与特异度分别为97.92%(47/48)和100.00%(34/34)。结论 甲状腺乳头状癌在超声上多表现为血流信号异常、钙化、后方回声衰减、晕环征等特征,超声弹性成像评分多为3~4分,超声弹性成像联合高频超声在其诊断中具有较高的应用价值。
Objective To explore the application value of ultrasound elastography combined with high-frequency ultrasound in the diagnosis of papillary thyroid cancer(PTC).Methods From January 2022 to June 2023,82 patients with suspected PTC were treated at Chinese People’s Liberation Army Joint Logistics Force 990 Hospital.All patients were given ultrasound elastography combined with high-frequency ultrasound examination to record ultrasound features.All cases were given pathological examination,and the pathological examination were used as the gold standard for diagnosis.Results Among the 82 patients,48 were PTC(cancerous group),accounting for 58.54%;and the other 34 were benign thyroid nodules(benign group),accounting for 41.46%.The proportion of morphological abnormalities,posterior echo attenuation,calcification,halo ring signs,unclear boundary and internal hypoechoics in cancerous group were 81.25%,83.33%,83.33%,83.33%,81.25% and 81.25%,which were significantly higher than 52.94%,47.06%,47.06%,41.18%,47.06% and 52.94% in the benign group(P<0.05).The highest systolic flow velocity in the cancerous group was significantly less than that in the benign group(P<0.05),and the resistance index and pulse index were also significantly higher compared with the benign group(P<0.05).The elastography score were mostly 3~4 in the cancerous group and 2 in the benign group,with a significant difference between the two groups(P<0.05).Forty-seven cases of PTC were diagnosed by ultrasound elastography combined with high frequency ultrasonography,and the sensitivity and specificity in diagnosis were 97.92%(47/48)and 100.00%(34/34),respectively.Conclusions PTC is often characterized by abnormal blood flow signals,calcification,posterior echo attenuation,halo sign and so on.The ultrasound elastography score is usually 3~4 points.Ultrasonic elastography combined with high frequency ultrasound has high value in diagnosis of PTC.
目的 探讨超声监测导向下早期肠内营养(EEN)在重症脓毒血症(SS)有创通气(IV)患者中的应用效果。方法 选取2021年2月—2023年11月连州市人民医院收入的115例SS-IV患者,依据随机数字表法分为对照组(n=57)、超声监测组(n=58)。所有患者均予重症监护病房(ICU)综合治疗,在此基础上对照组实施临床经验的传统肠内营养(EN)干预,超声监测组实施超声监测导向下EEN干预,均监测至治疗结束。统计两组IV时间、ICU停留时间、EN达标时间、EN不耐受发生率、相关并发症发生率,比较干预前、EN结束时营养状况[白蛋白(ALB)、总蛋白(TP)、前白蛋白(PA)]、序贯器官衰竭评分(SOFA)、急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分。结果 对照组剔除放弃治疗1例,死亡2例,纳入54例;超声监测组剔除放弃治疗1例,死亡1例,纳入56例。超声监测组EN达标时间[(40.18±8.46)h]、IV时间[(7.12±1.44)d]、ICU停留时间[(9.21±1.63)d]短于对照组[(46.03±10.15)h、(8.02±1.62)d、(10.18±1.54)d](t=3.288、3.082、3.206,均P<0.05)。EN结束时超声监测组SS-IV患者血清ALB[(32.05±3.13)g/L]、TP[(65.36±3.62)g/L]、PA[(0.24±0.06)g/L]高于对照组[(30.28±2.24)g/L、(63.28±4.24)g/L、(0.21±0.05)g/L](t=3.400、2.770、2.843,均P<0.05)。EN结束时超声监测组APACHEⅡ评分[(15.85±1.93)分]、SOFA评分[(7.42±1.64)分]低于对照组[(17.02±2.04)分、(8.35±2.03)分](t=3.091、2.648,均P<0.05)。超声监测组EN不耐受发生率[12.50%(7/56)]低于对照组[29.63%(16/54)],超声监测组相关并发症发生率[8.93%(5/56)]低于对照组[24.07%(13/54)](χ2=4.878、4.608,均P<0.05)。结论 超声监测导向下EEN干预应用于SS-IV患者,可改善患者病情与营养状况,降低EN不耐受及相关并发症发生风险,缩短恢复时间。
Objective To investigate the effect of ultrasound monitoring guided early enteral nutrition(EEN)in patients with severe sepsis(SS)and invasive mechanical ventilation(IV).Methods A total of 115 SS-IV patients admitted to Lianzhou People's Hospital from February 2021 to November 2023 were randomly divided into control group(n=57)and ultrasound monitoring group(n=58).All patients were given comprehensive treatment in intensive care unit(ICU).On this basis,traditional enteral nutrition(EN)intervention with clinical experience was implemented in control group,and EEN intervention guided by ultrasonic monitoring was implemented in ultrasound monitoring group.All patients were monitored until the end of treatment.IV time,ICU stay time,EN compliance time,incidence of EN intolerance,and incidence of related complications were analyzed in the 2 groups.Nutritional status [albumin(ALB),total protein(TP),prealbumin(PA)],sequential organ failure assessment(SOFA),acute physiology and chronic health evaluation Ⅱ(APACHEⅡ)were compared before intervention and at the end of EN.Results In control group,1 cases gave up,2 cases died,and 54 cases were included.In ultrasound monitoring group,1 case gave up,1 case died,and 56 cases were included.The EN compliance time [(40.18±8.46)h],IV time [(7.12±1.44)d] and ICU stay time [(9.21±1.63)d] of ultrasound monitoring group were shorter than those of control group [(46.03±10.15)h,(8.02±1.62)d,(10.18±1.54)d](t=3.288,3.082,3.206,all P<0.05).At the end of EN,serum ALB[(32.05±3.13)g/L],TP[(65.36±3.62)g/L],PA[(0.24±0.06)g/L] of SS-IV patients in ultrasound monitoring group were higher than those in control group [(30.28±2.24)g/L,(63.28±4.24)g/L,(0.21±0.05)g/L](t=3.400,2.770,2.843,all P<0.05).At the end of EN,APACHEⅡ scores [(15.85±1.93)points] and SOFA scores [(7.42±1.64)points] of ultrasound monitoring group were lower than those of control group [(17.02±2.04)points and(8.35±2.03)points](t=3.091,2.648,all P<0.05).The incidence of EN intolerance in ultrasound monitoring group [12.50%(7/56)] was lower than that in control group [29.63%(16/54)],and the incidence of related complications in ultrasound monitoring group [8.93%(5/56)] was lower than that in control group [24.07%(13/54)](χ2=4.878,4.608,all P<0.05).Conclusions EEN intervention guided by ultrasonic monitoring in SS-IV patients can improve the nutritional status of patients,reduce the risk of EN intolerance and related complications,shorten the recovery time,and reduce the progression of patients' disease.
目的 探讨高频超声对小儿梅克尔憩室所致肠梗阻的诊断价值。方法 选取广州市妇女儿童医疗中心2018年1月—2023年12月经手术证实的由梅克尔憩室引起的肠梗阻患儿41例作为研究对象,回顾性分析患儿临床资料及超声表现,并与术中所见和病理结果进行对照。结果 41例患儿,发病平均年龄为(3.97±3.69)岁,其中男32例、女9例。术前超声诊断肠梗阻38例,诊断符合率为92.7%;诊断梅克尔憩室所致肠梗阻9例,诊断符合率为21.9%。术中诊断梅克尔憩室索带卡压肠管24例,腹内疝8例,肠扭转1例;肠套叠10例;梅克尔憩室炎症、粘连6例,粘连穿孔1例;憩室内异物并穿孔1例。结论 高频超声对小儿肠梗阻有重要的诊断价值,仔细探查可以明显提高梅克尔憩室所致肠梗阻的临床诊断率,为临床尽早手术提供重要依据。
Objective To investigate the diagnostic value of high frequency ultrasound for intestinal obstruction caused by Meckel's diverticulum in children.Methods From January 2018 to December 2023,41 children with intestinal obstruction caused by Meckel's diverticulum were selected as the study objects.The clinical data and ultrasound images of the children were analyzed retrospectively,and compared with the intraoperative and pathological results.Results In 41 patients,the average age of onset was(3.97±3.69)years ,including 32 males and 9 females.Preoperative ultrasonic diagnosis of intestinal obstruction in 38 cases,diagnosis coincidence rate was 92.7%.Intestinal obstruction caused by Meckel's diverticulum was diagnosed in 9 cases,the diagnosis coincidence rate was 21.9%.During the operation,24 cases of Meckel's diverticulum intestinal compression were diagnosed,8 cases of abdominal hernia,1 case of intestinal torsion,and intussusception of 10 cases.Meckel's diverticulum had inflammation and adhesion in 6 cases and adhesion perforation in 1 case.A case of foreign body in diverticulum with perforation.Conclusions High-frequency ultrasound has an important diagnostic value for intestinal obstruction in children.Careful exploration can significantly improve the clinical diagnosis rate of intestinal obstruction caused by Meckel's diverticulum,and provide an important basis for early clinical operation.
目的 应用高频超声观察眼轮匝肌的解剖信息和动态特征,探究肉毒毒素注射前超声评估的可行性,为个体化、精准化的治疗提供可能,以实现更加安全、更加高效的治疗效果。方法 采用高频超声获取40名20~30岁健康志愿者的双侧80条眼轮匝肌的长轴、短轴切面声像图,观察其全程形态、内部回声,并测量外眦水平眼轮匝肌最外侧缘与外眦之间的距离、外眦水平眼轮匝肌最厚处的前后径、外眦水平眼轮匝肌最厚处与表皮之间的距离,并对数据进行统计学分析。结果 高频超声可以清晰地显示眼轮匝肌全程的走形和整体肌束结构。微笑时可见外眦外侧的眼轮匝肌向内收缩,并出现不同程度的增厚。男性和女性外眦水平眼轮匝肌最外侧缘与外眦之间的距离分别为左侧(27.50±2.58)(25.32±2.17)mm,右侧(27.35±2.15)(25.11±2.08)mm;外眦水平眼轮匝肌最厚处的前后径分别为左侧(1.055±0.209)(0.770±0.172)mm,右侧(1.010±0.171)(0.775±0.162)mm;外眦水平眼轮匝肌最厚处与表皮之间的距离分别为左侧(2.450±0.274)(2.860±0.375)mm,右侧(2.430±0.252)(2.825±0.424)mm。上述3种指标在左右侧对比差异无统计学意义(P>0.05)。与男性对比,女性外眦水平皮下组织较厚、眼轮匝肌较薄,其最外侧缘与外眦之间的距离较短(P<0.05)。结论 高频超声为观察青年人群眼轮匝肌结构的有效影像学工具,可用于肉毒毒素注射前的面部评估。
Objective To observe the anatomical information and dynamic characteristics of the orbicularis oculi muscle by high-frequency ultrasound,to explor the feasibility of ultrasound evaluation before botulinum toxin injection,and to provide the possibility for personalized and precise treatment to achieve safer and more efficient therapeutic effects.Methods High frequency ultrasound was used to obtain long axis and short axis sectional ultrasound images of 80 bilateral orbicularis oculi muscles from 40 healthy volunteers aged 20-30.The overall morphology and internal echoes were observed,and the distance between the outermost edge of the orbicularis oculi muscle and the outer canthus,the anterior posterior diameter of the thickest part of the orbicularis oculi muscle at the outer canthus level,and the distance between the thickest part of the orbicularis oculi muscle and the epidermis at the outer canthus level were measured.Statistical analysis was performed on the data.Results High frequency ultrasound can clearly display the entire course of the orbicularis oculi muscle and the overall muscle bundle structure.When smiling,the orbicularis oculi muscle on the outer side of the outer canthus can be seen to contract inward and show varying degrees of thickening.The distance between the outermost edge of the orbicularis oculi muscle and the outer canthus of males and females were(27.50±2.58)(25.32±2.17)mm on the left side and(27.35±2.15)(25.11±2.08)mm on the right side,respectively.The anterior posterior diameters of the thickest part of the orbicularis oculi muscle at the level of the outer canthus were left(1.055±0.209)(0.770±0.172)mm and right(1.010±0.171)(0.775±0.162)mm,respectively.The distance between the thickest part of the orbicularis oculi muscle at the level of the outer canthus and the epidermis were(2.450±0.274)(2.860±0.375)mm on the left side and(2.430±0.252)(2.825±0.424)mm on the right side.There was no statistically significant difference in the comparison of the above three indicators on the left and right sides(P>0.05),while there was a statistically significant difference in the mean values of both males and females(P<0.05).Compared with males aged 20-30,females had thicker subcutaneous tissue at the level of the outer canthus and thinner orbicularis oculi muscle,with a shorter distance between the outermost edge and the outer canthus. Conclusions High frequency ultrasound is an effective imaging tool for observing the structure of the orbicularis oculi muscle in young population,and can be used for facial assessment before botulinum toxin injection.