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广州医药杂志服务号
论著

小针刀、局部浸润麻醉及其联合疗法治疗腰椎间盘突出症的临床研究

A clinical study on acupotomy,local infiltration anesthesia,and their combined use for lumbar disc herniation

:606-612
 
      目的 系统比较小针刀、局部浸润麻醉及两者联合疗法治疗腰椎间盘突出症(LDH)的临床疗效。方法 采用前瞻性随机对照设计,选取2023年1月—2025年1月收治的120例保守治疗无效的LDH患者,随机分为小针刀组(A组,n=40)、局部浸润麻醉组(B组,n=40)和联合治疗组(C组,n=40)。A组实施标准化小针刀松解术,采用“三点九刀”布点法松解粘连组织;B组采用超声引导下椎间孔外口及关节突关节囊周围利多卡因联合曲安奈德浸润麻醉;C组实施“麻醉-松解序贯疗法”(即先B组方案,后A组方案)。比较三组治疗前后视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、腰椎活动度(ROM)、表面肌电图(sEMG)、疼痛压力阈值(PPT)及改良Macnab优良率。结果 治疗后,三组VAS、ODI评分均较治疗前下降(P<0.001)。组间比较显示,C组VAS(2.08±0.90分)、ODI(14.65±3.70分)改善显著优于A组(3.80±1.20分,21.00±4.25分)和B组(3.93±1.15分,22.10±4.65分)(均P<0.05),A、B两组间无统计学差异(P>0.05)。C组在腰椎前屈ROM(67.78±9.18°)、竖脊肌静息sEMG比值(0.19±0.05)、腰椎旁PPT(4.60±0.91 kg/cm2)上亦显著优于A、B两组(均P<0.05)。改良Macnab评价显示C组优良率达85.00%(34/40),高于A组的52.50%(21/40)和B组的55.00%(22/40)(P<0.05)。结论 小针刀与局部浸润麻醉单一疗法对LDH均有效,但联合应用可产生多模式协同效应,通过阻断疼痛传导、调节炎性微环境和改善生物力学失衡,在缓解疼痛、促进功能恢复及改善客观生理指标方面均展现出显著优势,为中西医结合治疗LDH提供了更优化的创新性方案,具有重要临床推广价值。
      Objective To systematically evaluate and compare the clinical effectiveness and mechanistic actions of acupotomy,local infiltration anesthesia,and their combination in treating lumbar disc herniation(LDH).Methods This prospective,randomized controlled trial included 120 LDH patients unresponsive to conservative management,admitted between January 2023 and January 2025.Participants were randomly allocated to three groups:the Acupotomy Group(Group A,n=40)receiving standardized acupotomy release with a “three-point nine-needle” technique to address adhesions;the Local Infiltration Anesthesia Group(Group B,n=40)receiving ultrasound-guided infiltration of lidocaine combined with triamcinolone acetonide around the extraforaminal outlet and facet joint capsule;and the Combined Therapy Group(Group C,n=40)undergoing a sequential “anesthesia-release” protocol(first applied Group B therapy then Group A therapy).Assessments conducted before and after treatment included the Visual Analog Scale(VAS),Oswestry Disability Index(ODI),lumbar range of motion(ROM),surface electromyography(sEMG),pain pressure threshold(PPT),and the modified Macnab criteria.Results Following treatment,significant reductions from baseline were observed in VAS and ODI scores across all three groups(P<0.001).Between-group comparisons indicated that Group C achieved significantly greater improvement in VAS(2.08±0.90)and ODI scores(14.65±3.70)compared to Group A(3.80±1.20;21.00±4.25)and Group B(3.93±1.15;22.10±4.65)(all P<0.05),with no significant difference between Groups A and B(P>0.05).Group C also showed superior outcomes in lumbar flexion ROM(67.78±9.18°),the resting sEMG amplitude ratio of the erector spinae muscles(0.19±0.05),and paravertebral PPT(4.60±0.91 kg/cm2)compared to the other two groups(all P<0.05).Based on the modified Macnab criteria,the excellent-good rate was 85.00%(34/40)in Group C,significantly higher than the rates of 52.50%(21/40)in Group A and 55.00%(22/40)in Group B(P<0.05).Conclusions While both acupotomy and local infiltration anesthesia as standalone treatments are effective for LDH,their combined application produces a multimodal synergistic effect.This integrated strategy,which concurrently interrupts pain signaling,modulates the local inflammatory milieu,and ameliorates biomechanical dysfunction,demonstrates significant advantages in pain relief,functional recovery,and normalization of objective physiological measures.The findings present an optimized and novel integrative approach for LDH management,highlighting its considerable potential for broader clinical adoption.
论著

TESSYS 技术对腰椎间盘突出症患者疼痛及功能的影响

The impact of TESSYS technology on pain and function in patients with lumbar disc herniation

:352-358
 
       目的  分析改良经脊柱内椎间孔镜系统技术(TESSYS)对腰椎间盘突出症患者疼痛及功能的影响,以期分析该术式优劣,丰富该研究领域。方法  回顾性选取2022年10月—2024年10月医院治疗的80例腰椎间盘突出症患者作为研究对象,根据治疗方式的不同划分为观察组(TESSYS技术治疗)和对照组(经皮椎间孔镜髓核摘除术治疗),每组各40例。观察两组患者疗效、手术时间、术中出血量、住院时间、透视次数、切口长度等情况。比较两组患者术前、术后6 h、术后1天、术后1周、术后1个月VAS评分情况,比较两组患者术前及术后1个月腰椎功能情况,包括Oswestry功能障碍指数(ODI)、腰椎曲度、腰背肌后伸活动度。比较两组患者术前及术后24 h的血清超敏C-反应蛋白(hs-CRP)、白细胞介素-6(IL-6)水平。结果   观察组患者疗效优于对照组(Z=-3.737,P<0.001)。交互效应下,两组疼痛因不同术式而随着时间增加而有所不同(P<0.05);时点效应下,观察组、对照组各组均随着时点增加疼痛随之减少(P<0.05);组间效应下,干预前、干预后1个月两组差异不明显,但是观察组疼痛干预后6 h(Z=-2.831,P=0.005)、干预后1天(Z=-3.253,P=0.001)低于对照组。术后1个月,观察组患者的ODI(Z=-4.804,P<0.001)低于对照组,而腰椎曲度(Z=-6.218,P<0.001)、腰背肌后伸活动度(Z=-7.014,P=0.001)高于对照组。术后24 h后,观察组患者的hs-CRP(Z=-5.671,P<0.001)、IL-6(Z=-3.262,P<0.001)低于对照组。结论  TESSYS相较于经皮椎间孔镜髓核摘除术在治疗腰椎间盘突出症时具有显著优势,可提高疗效,减少出血量,减轻疼痛,减少炎症反应,加快腰椎功能康复,缩短住院时间。
       Objective  The effect of modified transforaminal endoscopic spine system(TESSYS) on pain and function in patients with lumbar disc herniation was analyzed,so as to analyze the advantages and disadvantages of this procedure and enrich the research field.Methods  Retrospectively,80 patients with lumbar disc herniation treated in the hospital from October 2022 to October 2024 were selected as the study subjects.These patients were divided into two groups based on their treatment methods:the observation group(treated with TESSYS technology)and the control group(treated with percutaneous endoscopic discectomy).Each group consisted of 40 patients.The study evaluated the treatment efficacy,surgical duration,intraoperative bleeding volume,hospital stay fluoroscopy frequency,and incision length for both groups.Additionally,we compared the VAS  scores of  both groups before surgery,six hours post-surgery,one day post-surgery,one week post-surgery,and one month post-surgery.We also compared the lumbar function of both groups before surgery and 1 month post-surgery,including the Oswestry Functional Index(ODI),lumbar lordosis,and lumbar back muscle extension activity.Furthermore,we compared the serum levels of high-sensitivity C-reactive protein(hs-CRP)and interleukin-6(IL-6)in both groups before and 24 hours after surgery.Results  The therapeutic effect of the observation group was better than that of the control group(Z=-3.737,P<0.001).Under the interaction effect,the pain of the two groups varied with time due to different surgical procedures(P<0.05).Under the time effect,both the observation group and the control group showed a decrease trend in pain as the time to treatment increased(P<0.05).Under the inter group effect,there was no significant difference between the two groups before and 1 month after intervention,but the pain in the observation group was less than that in the control group at 6 hours after intervention(Z=-2.831,P=0.005)and 1 day after intervention(Z=-3.253,P=0.001).One month after surgery,the ODI(Z=-4.804,P<0.001)of the observation group patients was lower than that of the control group,while the lumbar curvature(Z=-6.218,P<0.001)and lumbar back muscle extension activity(Z=-7.014,P=0.001)were higher than those of the control group.Twenty-four hours after surgery,the hs-CRP(Z=-5.671,P<0.001)and IL-6(Z=-3.262,P<0.001)levels in the observation group were lower than those in the control groupConclusions  The improved  percutaneous transforaminal endoscopic technique  has  significant advantages over  percutaneous transforaminal discectomy in the treatment of lumbar disc herniation.It can improve efficacy,reduce bleeding,alleviate pain,reduce inflammatory reactions,accelerate lumbar functional recovery,and shorten hospitalization time.
临床诊疗

脊柱微创手术治疗腰椎间盘突出症的临床价值

:91-95
 
目的 分析在临床治疗腰椎间盘突出症过程中采取脊柱微创手术的价值。方法 回顾研究2019年2月-2021年2月本院的102例腰椎间盘突出症患者,按照电脑排序将患者分为参照组51例与研究组51例。其中,接受传统手术治疗的为参照组,接受脊柱微创手术治疗的为研究组,将不同方案下的效果进行对比。结果 研究组切口长度指标更低于参照组,术中出血量指标比较差异有统计学意义少于对照组,手术时间更短于参照组,比较差异有统计学意义(P<0.05)。研究组术后引流量指标均更低于参照组,术后活动时间及住院时间指标均更低于参照组,比较差异有统计学意义(P<0.05)。两组患者接受治疗前疼痛程度评分对比,无比较差异有统计学意义差异性(P>0.05),治疗后研究组患者疼痛评分均更低于参照组,比较差异有统计学意义(P<0.05)。研究组治疗后并发症发生概率5.88%更低于参照组的21.57%,比较统计差异比较差异有统计学意义(P<0.05)。结论 在临床治疗腰椎间盘突出症过程中采取脊柱微创手术效果良好,比较差异有统计学意义地降低患者手术损伤,缓解了患者手术疼痛感,促进患者尽快术后康复,防止并发症的发生,适合于临床中应用。
论著

自拟补肝益肾壮腰汤联合脊柱推拿及牵引对腰椎间盘突出症患者肌电图和腰椎功能的影响

Effects of Bugan Yishen Zhuangyao decoction combined with spinal massage and traction on EMG and lumbar function in patients with lumbar disc herniation

:78-82
 
目的 探讨自拟补肝益肾壮腰汤联合脊柱推拿、牵引对腰椎间盘突出症(LDH)患者肌电图和腰椎功能的影响及临床效果。方法 选取106例LDH患者采用随机数字表法分为观察组和对照组各53例。对照组行脊柱推拿及牵引治疗,观察组在此基础上加用自拟补肝益肾壮腰汤。记录2组患者治疗前及治疗3个月后的腰椎功能程度[Oswestry功能障碍指数(ODI)]、肌电图[平均功率频率(MPF)、中位频率斜率(MFs)、平均肌电波幅(AEMG)]、运动功能障碍程度[日本骨科协会下腰痛量表(JOA)]及疼痛程度[视觉模拟评分法(VAS)]评估结果差异。结果 治疗3个月后,2组JOA评分、VAS评分及各项肌电图参数(MPF、MFs、AEMG)均较治疗前有提升,且观察组均高于对照组(P均<0.05);ODI评分则较治疗前下降(P均<0.05),且观察组低于对照组(P<0.05)。结论 自拟补肝益肾壮腰汤联合脊柱推拿及牵引能明显改善LDH患者腰椎功能,促进肌力恢复、缓解肌肉疲劳、减轻疼痛,有较高的临床实用价值。
Objective To investigate the effect of self-made Bugan Yishen Zhuangyao decoction combined with spinal massage and traction on electromyography and lumbar function and clinical efficacy in patients with lumbar disc herniation (LDH). Methods A total of 106 patients with LDH were randomly divided into observation group and control group. The control group was treated with spinal massage and traction, and the observation group was treated with self-made Bugan Yishen Zhuangyao decoction on this basis. The degree of lumbar spine function [Oswestry disability index (ODI)], electromyography [mean power frequency (MPF), median frequency slope (MFS), average EMG amplitude (AEMG)], the degree of motor dysfunction [Japanese Orthopaedic Association (JOA) score] and the degree of pain [visual analog scale (VAS)] before and 3 months after treatment were recorded and compared. Results After 3 months of treatment, JOA score, VAS score and EMG parameters (MPF, MFS and AEMG) in the two groups were significantly higher than those before treatment, and those in the observation group were higher (P<0.05); ODI score was significantly lower than that before treatment (all P<0.05), and the observation group was significantly lower than the control group (P<0.05). Conclusions The self-made Bugan Yishen Zhuangyao decoction combined with spinal massage and traction can significantly improve the lumbar function of patients with LDH, promote the recovery of muscle strength, relieve muscle fatigue and pain, and with high clinical practical value.
论著

不同年龄段患者椎间孔镜下腰椎间盘突出症疗效分析

Analysis of curative effect of lumbar disc herniation under transforaminal endoscopy in patients of different ages

:73-76
 
目的 观察椎间孔镜下腰椎间盘突出症的近期疗效,分析不同年龄段对手术疗效的影响。方法 收集120例腰椎间盘突出患者,分成A、B、C三个研究小组:A青年组(年龄≤44岁)、B中年组(44岁<年龄<65岁)、C老年组(年龄≥65岁)。以术前、术后1天、术后3月、术后6月为界限,分析患者的疼痛视觉模拟量表(VAS)评分,并计算相对应的腰椎Oswestry功能障碍指数;术后1年用改良Macnab标准评价疗效优良率。结果 针对不同试验小组的VAS评分、ODI指数等进行对比分析:术后1天的对比差异不存在统计学意义(P>0.05);术后3个月、6个月比较差异有统计学意义(P<0.05),其中C组术后3月、6月VAS评分、ODI指数高于A、B组,差异有统计学意义(均P<0.05),A、B组间比较无统计学差异(P>0.05)。术后1年三组间疗效优良率比较无统计学差异(P>0.05)。结论 不同年龄段患者椎间孔镜的近期疗效显著,中青年患者恢复快,中期疗效好。
Objective To observe the short-term curative effect of transforaminal endoscopy for lumbar disc herniation, and to analyze the influence of different age on the curative effect. Methods 120 patients with lumbar disc herniation were collected, the study was divided into three groups: group A, group B and group C: group A (young adults, 44 years or older), group B (44 years or older) and group C (65 years or older). The visual analogue scale (Vas) scores of the patients were analyzed and the corresponding Oswestry index of the lumbar spine was calculated according to the preoperative, 1 day, 3 months and 6 months postoperatively. A modified Macnab was used to evaluate the rate of excellency and good results 1 year after operation. Results The Vas score and Odi index of different groups were compared. There was no statistically difference at 1 day after operation (P > 0.05). After 3 months and 6 months, there was statistically difference (P<0.05), among them, the VAS scores and Odi index of group C were higher than those of group B, the difference was statistically significant (P<0.05), there was no statistically difference between group A and group B (P > 0.05). There was no statistically difference between the three groups in the first year after operation (P > 0.05). Comparison of VAS score and ODI index among the three groups: there was no statistically difference at 1 day after operation (P>0.05); there was statistically difference at 3 months and 6 months after operation (P<0.05), among which VAS score and ODI index of group C were higher than those of group A and group B (all P<0.05), but there was no statistically difference between group A and group B (P>0.05). There was no statistically difference in the excellent and good rate among the three groups one year after operation (P>0.05). Conclusion The short-term curative effect of intervertebral foramina in patients of different ages is remarkable, the young and middle-aged patients recover quickly, and the medium-term curative effect is good.
临床诊疗

经椎间孔镜术及显微镜下髓核摘除术治疗腰椎间盘突出症的近期疗效分析

:124-128
 
目的 评价经椎间孔镜术和显微镜下髓核摘除术治疗腰椎间盘突出症的临床疗效及优缺点,并探讨该术式的有效性、安全性,以期找到更优的手术治疗腰椎间盘突出症方法及临床应用价值。方法 通过回顾性分析我院2019年1月—2019年12月经椎间孔镜下髓核摘除术及显微镜下椎板开窗减压髓核摘除术患者,总随访251例,其中椎间孔组229例,显微镜组22例。采集数据包括病例数、性别、年龄、手术时间、出血量及切口感染情况,术前、术后的JOA评分、VAS评分、ODI功能指数、改良MacNab标准,并对数据进行统计学分析。结果 椎间孔组手术采用局麻下进行,显微镜组采用全麻下进行,其中椎间孔镜组有2例患者因术中腰部剧痛不能配合完成,余患者手术完成顺利。椎间孔镜组平均病程5个月,手术时间(96±10)min,术中出血量(25.8±10.6)mL,术前JOA评分、VAS评分、ODI功能指数依次为14.23±3.08、6.08±1.64、30.18±7.92,术后JOA评分、VAS评分、ODI功能指数分别是22.65±1.58、1.77±0.5、19.67±3.89,改良MacNab标准为优150例,良42例,可26例,差9例,总优良率84.6%。显微镜组平均病程8个月,手术时间(45±10)min,术中出血量(62±10.6)mL,术前JOA评分、VAS评分、ODI功能指数依次为15.13±2.06、6.85±1.27、29.42±7.47,术后JOA评分、VAS评分、ODI功能指数分别是23.25±1.31、1.98±0.53、20.12±4.03。椎间孔镜组改良MacNab标准为优150例,良42例,可26例,差9例,总优良率84.6%;显微镜组改良MacNab标准为优17例,良2例,可3例,差0例,总优良率86.4%;两组患者性别、年龄与术前JOA评分、VAS评分、ODI功能指数相关性无统计学意义;9例椎间孔镜术后患者因效果差择期行显微镜下开窗手术治疗。结论 经皮椎间孔镜手术及显微镜下开窗减压髓核摘除手术治疗腰椎间盘突出症疗效均可靠,能有效改善患者下肢放射痛等临床症状,提高患者的生活质量及减轻功能障碍,但椎间孔镜组更具有微创、出血量少、术后恢复快等优势。
论著

不同针具在治疗腰椎间盘突出症的有效性与安全性的系统评估和网状 Meta 分析

A systematic assessment and network meta-analysis of the efficacy and safety of different needles in thetreatment of lumbar disc herniation

:469-485
 
       目的   评价现有关于干预组仅涉及不同针具针刺或联合常规针刺治疗腰椎间盘突出症系统评价的方法学质量,以比较不同针具针刺治疗腰椎间盘突出症的治疗效果。方法   通过CNKI(中国知网)、万方数据库、VIP(维普)、PubMed、Web of Science等数据库以及其他相关电子资源,对诊断、治疗腰椎间盘突出症的多种针灸技术进行全面的研究。使用AMSTAR2软件,对所有参与的系统性评估结果进行地分析,并根据不同的检测结果,确定文献筛选标准。通过Revman5.4和Cochrance风险偏倚工具,以及Stata16.0的网格Meta分析,挑选了3 381个满足纳入排除要求的随机对照试验。   以Stata 16.0统计软件制作排序图可知,杵针+电针的临床有效率SUCRA=81.6%排名第一;目测类比评分显示,银质针SUCRA(用于评估疗效的指标)=95%,排名第一。结论   根据现有的研究证据,杵针+电针以及银质针优于其他9种干预措施,但确切的结果仍需要大量的随机对照试验来证明。
       Objective  To evaluate the methodological quality of the existing  systematic evaluation of the intervention group involving only different needle sets of acupuncture or combined with conventional acupuncture in the treatment of lumbar disc herniation,in order to compare the therapeutic effect of different needle sets of acupuncture in the treatment of lumbar disc herniation.Methods  Through CNKI,Wanfang database,VIP,PubMed,web of  science and other  databases as well as other  relevant resources,a variety of acupuncture techniques for the diagnosis and treatment of lumbar disc herniation were comprehensively studied.Through the use of AMSTAR2 software,all participating systematic evaluation results were effectively analyzed,and according to different test results,which literature meets the requirements were determined.Through revman5.4,Cochrane risk bias tool,and grid meta-analysis of stata16.0,3 381 RCTs meeting the inclusion and exclusion requirements were selected.Results  According to the ranking chart made by stata16.0 statistical software,the clinical effective rate of pestle needle + electroacupuncture ranked first with sucra=81.6%.According to the visual analogy score,the silver needle sucra=95%,ranking first.Conclusions  According to the existing research evidence,pestle needle + electroacupuncture and silver needle are better than the other nine interventions,but the exact results still need a large number of randomized controlled trials to prove.
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