目的 分析、探讨正常压力性脑积水发病机制、临床特点、手术指征及疗效。方法 回顾性分析我院自2005年1月—2015年1月采用侧脑室-腹腔分流术治疗53例正常压力性脑积水患者临床资料。结果 随访0.5~3年,总有效率为79.2%,无效率为20.8%,不良反应发生率为5.6%,不同临床特点患者的疗效有显著性差异(P＜0.05)。结论 提高对正常压力性脑积水认识,尽早确诊,选用合适压力的分流管,及时行脑室-腹腔分流术,注意防治并发症,以提高手术疗效。

Objective To explore the pathogenesis, clinical features, operation indication as well as therapeutic effect of hydrocephalus with normal pressure. Methods 53 patients underwent the ventriculo-peritoneal shunt from our hospital from Jan 2005 to Jan 2015 were retrospectively studied. Results Follow-up period was 0.5 to 3 years. Total efficacy rate was 79.2%; The failure rate was 20.8%; The incidence rate of adverse reaction was 5.6%. There were significance statistically for therapeutic effect between different groups(P＜0.05). Conclusion It is important to strengthen the awareness and diagnosis for hydrocephalus with the normal pressure. The suitable shunt duct and the ventriculo-peritoneal shunt in time will decrease complications and improve surgical therapeutic effect.